LL-37 5mg

LL-37 is a cathelicidin-derived antimicrobial peptide (AMP) that plays a critical role in the body’s innate immune system. It is known for its potent antimicrobial properties, targeting bacteria, viruses, fungi, and biofilms. Additionally, LL-37 exhibits anti-inflammatory and tissue-repair properties, making it valuable in addressing chronic infections, wound healing, and immune regulation. This peptide has been widely studied for its ability to modulate the immune response and promote the regeneration of damaged tissues.

LL-37 engages immune modulatory pathways through interaction with pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs) and formyl peptide receptor-like 1 (FPRL1), resulting in the regulation of inflammatory cytokine release and chemotaxis in non-human test subjects. Additionally, it enhances angiogenesis and epithelial cell migration, contributing to wound repair processes. The peptide also plays a role in modulating the immune response in animal test subjects by neutralizing lipopolysaccharides (LPS), thus attenuating endotoxin-induced inflammatory pathways.

Research on LL-37 further reveals its bifunctional role in oncological contexts, where it may exert both tumor-suppressive and tumor-promoting effects, contingent upon the surrounding microenvironment. Due to its multifaceted biological activities, LL-37 is of significant interest in preclinical studies aimed at investigating its potential therapeutic applications in combating microbial resistance and modulating inflammatory responses in non-human test subjects.

Science-Backed Research

• Helps combat antibiotic-resistant infections (e.g., MRSA)
• Broad-spectrum efficacy against bacteria (gram-positive and gram-negative), viruses, fungi, and biofilms
• Modulates immune responses to reduce chronic inflammation
• Balances pro-inflammatory and anti-inflammatory cytokines for a healthier immune state
• Promotes angiogenesis and the migration of keratinocytes, essential for tissue repair
• Stimulates regeneration of damaged skin, mucosal tissues, and internal wounds
• Enhances gut barrier integrity, reducing intestinal permeability (“leaky gut”)
• Supports repair in chronic wounds, surgical sites, and areas of trauma

Properties

• Chemical Formula :C205H340N60O53
• Synonyms :Cathelicidin, ropocamptide, Bac4, Cathelicidin antimicrobial peptide 18
• Molar Mass :4493 g/mol
• CAS Number :154947-66-7
• PubChem :16198951
• Total Amount of the Active Ingredient :5mg (1 vial)
• Shelf Life :36 months