MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor)

Mechano Growth Factor which also goes by MGF, is a peptide hormone that is produced in muscles in a response to training. The peptide is an isoform of IGF 1. This means that it is comes from the same locus, or location, but are different in their transcription start sites. In most situations, MGF is more abundant in children and adolescence. As we age, we lose our ability to create the peptide on our own. This makes the synthetic version of this peptide the more viable option.

Unlike its PEGylated counterpart, MGF without PEG has a short half-life due to rapid enzymatic breakdown. It undergoes proteolytic degradation and receptor-mediated clearance, making it suitable for research applications requiring transient bioactivity.

MGF is typically in the muscle tissue. This also includes skeletal muscle and its main function is to proliferate muscle stem cells. These types of cells are also satellite cells. Because of its mechanisms Mechano Growth Factor can rapidly repair damage done to muscle and promote muscle growth. Within MGF there is a unique E domain in the C terminal.

In a newer development, MGF is even a possibility for preventing neuronal attribution and brain dysfunctions. However, these treatments are dose and age dependent. In a study done with Mechano Growth Factor, it showed up within the body after an hour. Not only that, it remained elevated for several weeks after the initial dose.

Neurogenesis

Neurogenesis is a process where neural stem cells or NCSs produce nervous system cells. In human adults, this occurs in two major areas of the brain, the subventricular and sub granular zones. Age, stress, disease, and exercise of an individual seem to drive this process. Overtime, stems cells in these regions of the brain tend to decline. It is important to note that they don’t completely disappear but that they are just less common.

So how does Mechano Growth Factor have anything to do with neurogenesis? As we age and start to lose our ability to create our own NSC. Therefore, by using MGF, can help in maintaining our neural stem cells at what is considered a youthful level.

In an ischemic brain model, MGF showed an ability to have neuroprotective effects. It has even shown potential to be more effective that IGF 1 in this category. In a study completed with aging mice, MGF demonstrated a prevention of neuronal attribution and brain dysfunction.

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis, or ALS, is a fatal neurodegenerative disorder. motoneuron degeneration typically characterizes it. Also known as destruction of nerve cells. The cells form part of a pathway where impulses pass from the brain or spinal cord to muscles or glands.

Benefits And Side Effects

Several benefits have been associated with Mechano Growth Factor because of its ability to active muscle stem cells in the muscle groups it is sited into. It then increases the synthesis of proteins that are necessary for tissue growth. MGF can activate the satellite cells which then triggers fusion to muscle fibers and reparation of injury. It is an essential peptide for muscle growth, recovery, and repair.

·        Improve Injury Recovery

·        Increase Muscle Growth

·        Multiplication of Muscle Fibers

·        Neuroprotective Effects

·        Brain Dysfunction Preventative

Many research trials have been conducted using MGF and found several positives. However, there are a few side effects to keep in mind while taking MGF. For one, a common side effect is hypoglycemia. It is known commonly as low blood sugar. It can be combated by making sure you are keeping an eye on your blood sugar levels. Another common but mild side effect is swelling of extremities. As long as dosing protocol is followed, you limit the possible side effects of MGF.

Dose & Protocol

When it comes to the correct dose for MGF the doses themselves are administered into the muscle groups you want to grow. The recommended dosage is 200mcg per day, this can be split into 2 injections. This peptide is made so that you can administer it either post workout, before bed or both. Dosages of up to 400mcgs have been reported administered in 4 separate injections timed throughout the day.

When eating right and working out isn’t enough and an injury occurs  introducing Mechano Growth Factor into your regimen of supplements for training will be the game changer. This way you can increase your gains and keep your muscles intact.

If you’re just starting out or are a seasoned bodybuilding athlete, then MGF peptide is perfect for you. You’ll be able to maintain muscle growth, improve recovery time and keep your brain functioning at optimal levels.